Preliminary scientific studies indicate conolidine may perhaps inhibit precise ion channels, minimizing neuronal excitability and limiting agony indicators. This mechanism is especially pertinent in neuropathic pain, where by abnormal signaling will cause persistent irritation. In addition, conolidine seems to impact G protein-coupled receptor (GPC

Researchers have just lately recognized and succeeded in synthesizing conolidine, a pure compound that displays guarantee as a strong analgesic agent with a more favorable security profile. Although the actual system of action remains elusive, it really is at this time postulated that conolidine could possibly have quite a few biologic targets. Pre